DDX58 anticorps

N° du produit ABIN7604629

L’anticorps Lapin Monoclonal anti-DDX58 a été validé pour WB et IP. Il convient pour détecter DDX58 dans des échantillons de Humain.

Aperçu rapide pour DDX58 anticorps (ABIN7604629)

Antigène: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp DDX58 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: ACEA-4

Détail du produit anti-DDX58 anticorps

Fonction: Anti-DDX58 Monoclonal Antibody

Attributs du produit: Anti-DDX58 Monoclonal Antibody (ABIN7604629). Tested in WB, IP applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human DDX58 Retinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000
IP 1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Détails sur DDX58

Antigène: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Autre désignation: DDX58

Sujet:

Synonyms: Histone H2AX,H2a/x,Histone H2A.X,H2AFX,H2AX,

Tissue Specificity: Ubiquitous. The mRNA is present at similar levels in viable and apoptotic cells, whereas the protein is dramatically highly expressed in apoptotic cells.

Poids moléculaire: 100-110 kDa

UniProt: O95786

Pathways: Activation of Innate immune Response, Hepatitis C